Non Evidence-Based Factors Influence Evidence-Based GuidelinesPDF german translation / full article
Summary: The scientific evidence of studies usually cannot be directly transformed into guideline-recommendations. For sound recommendations the guideline-group must first interpret and then integrate available studies in their variety of populations and differences of methodological quality. The view on studies of those working in the guideline group carries immense weight, particularly because the strength of a recommendation is also influenced by the voting of the group. In several instances this stands in contrast to the scientific evidence which should be base of a guideline. Some suggestions might contribute to a solution of this dilemma.