Nausea and Emesis in Cancer Patients

DOI: 10.3238/zfa.2015.0111-0116

german translation / full article

Georgia Schilling

Keywords: Sickness Vomiting Chemotherapy-Induced Emetic Potential Palliative Care

Summary: Until mid of the 90ties, sickness, nausea and vomiting were highly feared by patients undergoing chemotherapy. New supportive agents and their standardized, guideline-adapted use can help us to successfully get control of these symptoms. Due to the profile of side effects of new “targeted agents” in cancer treatment, fatigue became the front runner of adverse events. Nausea and emesis are the most frequently reported symptoms in palliative care – not only on active cancer treatment. But differently to the standards mentioned above, no standard algorithms exist in this palliative situation. It is important to reflect potential reasons for the symptoms, and to investigate their causes to initiate a successful antiemetic therapy. Knowledge of pathophysiological context and receptor profile of the most commonly used antiemetics may help to avoid useless or even harmful combinations.

(State: 18.03.2015)

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