Sulfasalazine in Persistent Diarrhoea After Unspecific Dysenterygerman translation / full article
Is it allowed to give Sulfasalazine or Mesalazine for about 2 weeks in case of a patient having a acute persistent diarrhea, resistant to Loperamide for 4 days, but showing no bloody or mucous stools?
The pro-drug Sulfasalazine and its component Mesalazine are approved for the treatment of chronic inflammatory bowel diseases. But in a few, very small studies a positive effect has been shown also in unspecific chronic bowel diseases. Their role in acute diarrhea is not studied.