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Sulfasalazine in Persistent Diarrhoea After Unspecific Dysentery

german translation / full article

Simon Kostner

Question

Is it allowed to give Sulfasalazine or Mesalazine for about 2 weeks in case of a patient having a acute persistent diarrhea, resistant to Loperamide for 4 days, but showing no bloody or mucous stools?

Answer

The pro-drug Sulfasalazine and its component Mesalazine are approved for the treatment of chronic inflammatory bowel diseases. But in a few, very small studies a positive effect has been shown also in unspecific chronic bowel diseases. Their role in acute diarrhea is not studied.


(State: 17.12.2013)

Latest Issue 9/2020

In Focus

  • Clinical Characteristics of SARS-CoV-2 Tested Patients
  • Urinary Incontinence in Family Practice
  • Challenges in Southern Bavarian Primary Care Practices During the COVID-19 Pandemic