Measurement of Glucose: Serum versus Plasma

DOI: 10.3238/zfa.2020.0443-0446

german translation / full article

Manfred Eissler

Keywords: glucose glycolysis plasma preanalytics serum

BackgroundThe renaming of “glucose” in “fasting plasma glucose” in the respective guideline of the Joint Federal Committee has resulted in organizational and logistical changes for community physicians and laboratories. The aim of this study was to evaluate the equivalence of the measurement of blood glucose in serum and in plasma in an outpatient context. MethodsFrom 112 blood samples, both serum and plasma were obtained to measure the glucose value. The samples were taken in community medical practices and the samples were analyzed in the laboratory on the same day.ResultsOn average, the serum glucose values are above the plasma glucose values. The evaluation of the linear regression and the regression according to Passing-Bablok shows that the two methods are at least equivalent if the pre-analytical requirements are observed.ConclusionsThe method of glucose measurement required in the guidelines should be reconsidered.Keywordsglucose; glycolysis; serum; plasma; preanalytics

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(State: 13.11.2020)

Latest Issue 11/2020

In Focus

  • How Useful is the Examination of Complete Blood Count in Healthy Adults?
  • Measurement of Glucose: Serum versus Plasma
  • Quality Management in Outpatient Teaching Practices