Serenoa Repens (Saw Palmetto) for Benign Prostatic Hyperplasia
DOI: 10.3238/zfa.2021.0003-0006german translation / full article
QuestionAlpha-receptor-blockers are recommended as first-line therapy of lower urinary tract symptoms (LUTS) due to benign prostatic syndrome. This treatment is frequently accompanied by adverse effects like hypotension, dizziness and even an increased risk for falls. Therefore the question may be raised whether the frequently recommended phytotherapeutic remedies like e.g. Serenoa repens are a viable alternative. AnswerStudy results regarding the effectiveness of Serenoa repens are inconsistent. There are some positive randomized controlled trials, which show a favourable effect on the number of nocturnal voids and quality of life, but the effects are minor compared to placebo. On the other hand, direct comparison does not convincingly show an advantage of alpha-receptor-blockers over Serenoa repens. Therefore, after information of the patient about the inconsistent study data, a therapeutic trial with Serenoa repens seems well justified.